Can someone guide me on how I can program Skywalker esc with Pixhawk 2.4.8 for RC plane?
You need a program card like this for Skywalker V1 ESCs or like this for Skywalker V2 ESCs or you can program them with a radio controller like described in the manual.
This video might help. I’m about to try and calibrate a pair of Skywalkers with a Matek F405 Wing V2.