RP4 and Pixhawk mavlink connection "link 1 down", overclock issues

Hi, this is more a report than a question, recently I pass a hard time trying a Raspberry to communicate with Pixhawk throught Telemetry/UART. After a lot of checks finally tryed in a fresh installation… and everything work OK, but I have to export all my files to the new image, luckly, since I use overclock for a little push in some process, that was my first modification, tryed again and “Link 1 Down” come back, I suppose this is more a problem concern to Raspberry but maybe someone experience this before and have a workaround.