I’m nearly certain I’m using 4.5.7 on my own Cube Orange without issue (it’s been a while since I fired it up, but not so long that 4.5.7 wouldn’t be the firmware on it).
Might be worth flashing ArduPlane and then back to Rover to get a pretty thorough wipe of the entire board.
I have an Orange+ sitting in the corner with V4.5.7 has not been powered up for 6+ months. Just connected it to the same PC as the Orange and same issue. But agree very strange. Yesterday I did uninstall Mission planner and remove all the folders I would find and reinstalled.