This should be no problem. As long as the rear props are higher than the front props. This way the propwash of the front motors will not affect the rear motors,when tilting/flying forwards.
Yes I have tested it. The last vehicle I flown with a similar motor configuration, was my mini talon quadplane. Before that a copter with a pusher motor and once a copter with front and back motor on one level and left right motor 50cm below. You have to make sure the FC is level when the copter is on the ground, of course.