Vtol without RC and Land mode on plane

Has been almost 10 year that I’m playing with Ardupilot but I still have lot of questions.

Normal 3 axis plane fully setup with arduplane. If I want operate fully without RC, can I perform take off without setup a mission ?

How the land mode works in plane? how it could perform safety landing without knowing the landing approach? What happen if Failsafe is set to LAND?

on a Vtol plane, fully setup with arduplane. How can I operate without RC? In particular, can I perform Vtol take off, transition and flying it in guided mode without using a mission and without using an RC?

Apologies for nob questions but I always had the radio in the loop and most of the operations are performed using the RC.

Cheers,

Lorenzo