Pixhawk suitability for 100kg drone

Hello everyone,
I am working on a big project of mine of making a heavy drone probably around 100kg. The doubt i have is that if pixhawk will be able to fly at this extreme conditions or i will have to add external sensors.

thanks

Flown twice as heavy OEW (before payload)
So it would be fun to know why you think the laws of physics or PID loops won’t work for something big and sluggish while it works for a racing quad.

This is a Hex Cube / Pixhawk 2.1 running ArduPilot: https://www.wired.com/story/boeing-delivery-drone/