Matek 405 CTR COMUNICATION PROBLEMS WITH PC

I’m trying to use Matek 405 CTR with copter 4.0. I flashed without problems , connect and run through set up. But, when disconnecting and connecting again next day, looks that the controller can be connected but not data are showed in set up. It’s like no real comunication between controller and ardupilot
Only way was to flash again and start from cero. It happened several times. Could someone help?
Thanks in avance