Holybro Pixhawk 4 any good for VTOL in 2024?

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Unless you’re using some cheap clone, the Pixhawk 4 (by Holybro) uses an F765. Unless you’re more specific about your use case, no one can give you a recommendation that’s worth anything.

Literally any supported autopilot will work on a “fixed wing or VTOL” platform. You’ve said nothing about vehicle size or the feature set you wish to use.

And judging a book by its cover is very poor practice. There are much more advanced autopilots with possibly higher build quality that appear as bare PCBs.

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