It’s hard to say exactly, but let’s assume for a moment that your flight controller is perfectly level with the wing chord line. It’s normal that most planes will fly with a few degrees nose up attitude. How much will depend on the plane, the wing, the power setting, etc.
What I do is level everything to zero/flat during the initial calibration. I know that by doing this in FBWA my plane will probably slowly descend, but at least that way it’s safe, and when I pull back the throttle for approach or land (CTOL or VTOL) the plane won’t get too slow.
Once I have the plane flying I’ll fly in FBWB or Cruise mode for a bit. This will hold altitude and the FC will find the proper attitude for me. Then I go back and look at the log and set PTCH_TRIM_DEG based on what the FC did in flight.