Big RC trim offset between motors

I have big offsets between motors rc trim after esc calibration with arducopter

Could you say if its normal ?

No, that does not sound normal.

If you gave some more information we might be able to see why.
Is your copter balanced?

The drone is balanced, I think that trims was generated by arducopter ESC

Should I set same value than ppm centre throttle in blheli suite ?

Any ohter advise will be appreciated