In many cases you do not need to edit anything, the file already configures the system the way you need. But you still should confirm the changes.
If you have a different RC receiver you need to edit the RC receiver file.
If you have a different ESC, or need different ESC settings, for an octo for example you need to edit the ESC file.
The same for GNSS and the other files.
The mag calibration is specific to your vehicle you can not use the mag calibration from my vehicle in yours. But the setup can be reused, unless you require 3 IMUs instead of 2.
If that is complicated, we do offer paid consulting to customise your system to your needs.