Vtol wrong calibration of esc because wrong motor signal in ardupilot

Hi, I have been having a big problem with my vtol UAV, I can’t calibrate my ESC’S because when I put my throttle up, the signal of Motor 1, motor 2, motor 3 and motor 4 are not the same, also I put the ardupilot in QSTABILIZE, QHOVER QLOITER, but in any of those cases I find a solution, just when I put the throttle in the botton, the four motors are in "1100 ", but when I put it up, motor 1 is 1200, motor 2 1356, motor 3 1450, motor 4 1849, but if I repeat the process, those values change again, for that reason I cannot calibrate the esc, and for the same reason I can’t fly propertly the UAV.