Multiple crashes in auto mode quadcopter

the drone crashed three times in auto modes, sometime it works nicely in auto mode but failes in guided or auto mode all happened in auto mo

de, 2 times c3 motor rcou went high and the diagonally opposite low and once c1 went high and diagonally opposite c2 low,ardupilot version is 4.6.0

below is link for log file

Start by updating to ArduCopter 4.6.3.
Have you tuned the notch filter? Have you tuned the altitude controller?

no only initial tune parameters from mission planner, but it flies perfectly in loiter like butter

Sorry, but the crashes are a proof that it is not performing that well.
The good news is it can fly a lot better when correctly configured.

Configure the notch filter and the altitude controller like described in the ArduCopter documentation

can u please look at the log file once, i have doubt on ESC desync, plz help me, i will go through notch filtering also

Which ESCs do you use? with which firmware version? What are their settings?
How are they connected to the FC? Which motors do you use? how big are the props?

reflex drive 65A esc with PWM output to FC, firmware 4.6.0, cube orange plus, mn7005 230kv, 26inch props

That is a big and expensive setup!

On that kind of setup you should use AMC software to guide you through configuration steps in such a way that you do not “forget” to do any of the important steps