Calibration is not required with Dshot protocol. It will be the Low RPM Power Protect.
With regards to which Dshot protocol to run there are several variables there having to do with timing and the combination of FC and ESC. Some configurations won’t run Dshot150 for example but Dshot600 works fine. There are additional parameters in 4.2 to play around with. Want to see how complicated it can get? Check out this thread.Start at the end.
The dreaded Design Of Experiments I used to despise when I was a Test Engineer 