No problems Dave.
I ran that combination through ecalc, and that should be fine. The 10x6 will likely not have enough pitch and make to much thrust, if you look at the table at throttle 84% and then across, you'll see that your making 1139g of thrust at 68kmh airspeed. (77kmh pitch speed) That's about 2-3x as much thrust as I'd expect you to need to have at that speed with cruise around 68kmh. That 100km long range FX was only using around 350-400g of thrust, but at around 50kmh.
So a 10x6 will fly, and also takeoff and climb well, but it won't be very efficient at cruise. A 10x8 will be better on a quadplane setup to optimise cruise, if not maybe even more, or otherwise you might have to go down to a 9" diameter. You'll notice on the 10x8 it gives some warning's regarding stalling prop on the ground, but because of the QP we don't need to worry about it, as explained previously.
By the way ecalc is a good way to get your bearings around motors and props