to run a high voltage, motor needs a good quality winding.
if you are talking about FPV Quad, almost all motor for FPV Quad are now very good and can take 6s, even it is have high kv, like 2650kv.
for that motor, i dont have any confidence running it on 6s. But if you wanna try, you can try it using throttle limit and use smaller propeller first.